In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. Despite the growing body of research suggesting some link between COVID-19 and blood type, experts say these studies don't change much for the individual. Most humans fall into one of four blood groups: A, B, AB or O. While there are several theories, researchers don't yet know what mechanism could explain the link between different blood groups and Covid-19. "I don't think this supersedes other risk factors of severity like age and co-morbities and so forth," added Sekhon, who is also a clinical assistant professor in the Division of Critical Care Medicine and Department of Medicine at the University of British Columbia. It makes very little difference to most people's daily lives unless you have to have a blood transfusion. A Danish study found that among 7,422 people who tested positive for Covid-19, only 38.4% were blood type O -- even though, among a group of 2.2 million people who were not tested, that blood type made up 41.7% of the population. In the Danish study, researchers analyzed data on Danish individuals who were tested between February 27 and July 30, and the distribution of blood types among those people was compared with data from people who had not been tested. "If you're type A blood, you might be at a slightly higher risk than if you're type O. And several other peer-reviewed studies reinforce these findings. Some people who test positive for COVID-19 develop tiny blood clots that cause reddish or purple areas on the toes, which can itch or be painful. And that the worst thing that can happen is that people let their guard down,” Silverstein says. When these antigens come into contact with a pathogen or other unfamiliar substance, they trigger an immune system response. Both studies were published in the journal Blood Advances. According to their data, those with O blood type are between 9-18% percent less likely than individuals with other blood types to have tested positive for COVID-19. Still, the larger study did find that Type O blood was between 9 and 18 percent less likely to test positive for COVID-19 when compared to the other blood types… What's more, 95 percent of COVID-19 deaths in the U.S. have occurred in adults 50 and older. AARP members receive exclusive member benefits & affect social change. Research has shown that people with type O blood are more likely to get seriously ill from cholera than others who come down with the illness; and type O blood has been shown to offer some protection against severe malaria. Small blood clots can become lodged in tiny blood vessels. Certain blood groups less likely to get COVID-19. www.aarp.org/volunteer. The retrospective study found that there were more people with blood type A, B, and AB who tested positive than type O. Even still, experts caution that the accumulating evidence on this subject shouldn't influence everyday medical or public health decisions. These new findings—the first to identify statistically significant susceptibility genes for the severity of COVID-19—come from a large research effort led by Andre Franke, a scientist at Christian-Albrecht-University, Kiel, Germany, along with Tom Karlsen, Oslo … ", Residents in Italian town reflect on life one year under pandemic, Hear why this expert is optimistic about vaccines' efficacy, CNN finds evidence China is advancing theory that the virus originated in a lab in Maryland, Editor of medical journal explains how Russia's vaccine works, This 'critical' component for Covid-19 vaccines is in short supply, Coronavirus cases in this UK city are 'dramatically' decreasing, Canada's elderly are 'terrified' vaccines may not come soon enough, Cubans face an impossible choice: Go hungry or risk virus, WHO Wuhan mission finds possible signs of wider original outbreak in 2019, Covid-19 vaccine rollout is a much-needed win for the UK, Here's what happened to 2M doses of hydroxychloroquine the US sent Brazil (August, 2020), 'Sweetheart clause' allows couples to reunite amid pandemic, Australian Open changes Covid-19 policy, eliminating fans, See how Hong Kong will celebrate Lunar New Year amid pandemic, See inside a key component of Israel's world-beating vaccination program. By contrast, type O blood seemed to lead to a reduced risk, with 26% of the infected cases versus 34% of healthy people. That previous genetic study, paired with the two new studies in Blood Advances, are "suggestive that this is a real phenomenon that we're seeing," said Adalja, whose work is focused on emerging infectious disease. They found that people with type O blood had a lower risk for contracting the coronavirus (SARS-CoV-2) compared to those with type A, B or AB. Blood type is not associated with a severe worsening of symptoms in people who have tested positive for COVID-19, report Harvard Medical School researchers based at Massachusetts General Hospital. People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. Comments: 0. Visit today. Values represent risk differences for each blood type relative to the reference groups: O for ABO and positive for Rh(D). “They are at risk for COVID, just a little bit lower than type A.… That doesn't mean that [type] O is zero risk.”. Once you confirm that subscription, you will regularly Recent studies have suggested that people's blood types may affect their risk of contracting the COVID-19 virus or developing a serious … In the next 24 hours, you will receive an email to confirm your subscription to receive emails receive communications related to AARP volunteering. You will be asked to register or log in. "I would never tell someone who is type O that they don't have to wear a mask, or they don't have to do social distancing, or they don't have to wash their hands frequently,” says Roy Silverstein, M.D., professor and chair of medicine at the Medical College of Wisconsin Division of Hematology and Oncology, who was not involved in the studies. Correction: A previous version of this story inaccurately reported how many of the people who tested positive in the Danish study were blood type O. related to AARP volunteering. As for the novel coronavirus that causes Covid-19, "We need to figure out the mechanism and understand it at the molecular level to be able to say for sure how this is occurring -- that this is really the O blood type and not something that kind of tracks with O blood type," Adalja said. People with blood type O may have lower risk of COVID-19 infection and severe illness, two new studies suggest. "There's more science to be done here, but it seems to me that there's more evidence accumulating for this hypothesis. "We do not know whether this is some kind of protection of group O, or whether it's some kind of vulnerability in the other blood groups," he said. And certain blood types may be better at fighting off certain foreign invaders than others. (CNN) People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. In the other study, researchers in Canada found that among 95 patients critically ill with Covid-19, a higher proportion with blood type A or AB -- 84% -- required mechanical ventilation compared with patients with blood group O or B, which was 61%. Javascript must be enabled to use this site. For instance, research suggests that people with blood type O appear to be more susceptible to norovirus infection. Experts say more research is needed. You must be logged in to leave a comment. Having O and rhesus-negative, or Rh–, blood was associated with a slightly lower risk for COVID-19 infection and severe illness or death, according to research published in … “There's a fairly decent amount of existing literature beyond SARS-CoV-2” that certain blood types can play a role in disease risk and severity, says Joel Ray, M.D., a clinician scientist and professor at St. Michael's Hospital in Toronto and lead author of the study published in Annals of Internal Medicine. People with type A blood seem to be at higher risk for severe COVID-19, while those with type O blood appear to be less likely to test positive for COVID … again. Here's how to find out yours, The New England Journal of Medicine in June. The reasons for this link aren't clear and more research is needed to say what implications, if any, it has for patients. In fact, type O blood were about 13% less likely to test positive … Blood type may also influence norovirus susceptibility. “Clotting is always a good thing if you cut yourself, but it's a bad thing, generally, if you get a really bad infection [because it] activates the clotting cascade and tends to activate clotting in small blood vessels,” he says. And though researchers still don't know why or how blood type may interact with SARS-CoV-2, a better understanding could “lead to discovering new pathways or new targets for treatment,” he adds. Sekhon said it could be explained by people with blood type O having less of a key clotting factor making them less prone to coagulation problems in the blood. For the latest coronavirus news and advice go to AARP.org/coronavirus. Experts say more research is needed. Coronavirus news -- A person's blood type may affect their risk for COVID-19, the disease caused by the new coronavirus, researchers report. The findings of the two new studies provide "more converging evidence that blood type may play a role in a person's susceptibility to Covid infection and their chance of having a severe bout of Covid-19," said Dr. Amesh Adalja, senior scholar at the Johns Hopkins University Center for Health Security in Baltimore, who was not involved in either of the studies. (CNN)People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. Most of the value in the research, Silverstein says, is to learn more about the new virus that has so far infected almost 68 million people worldwide, and how the body responds to it. Or it could be linked to genes associated with blood types and their effect on receptors in the immune system. "I think this has scientific interest, and when we find out what the mechanism is, perhaps we're able to use that proactively in some way in regard to treatment.". to search for ways to make a difference in your community at WW will help you build a customized weight loss plan. You'll start receiving the latest news, benefits, events, and programs related to AARP's mission to empower people to choose how they live as they age. A large study adds to evidence that people with type O or Rh−negative blood may be at slightly lower risk from the new coronavirus. The blood type–infection connection is not unique to the coronavirus. You are leaving AARP.org and going to the website of our trusted provider. by Rachel Nania, AARP, December 8, 2020 When this happens close to the skin, it can result in a rash. They also observed that individuals with type O blood had a slightly lower risk for getting severely ill or dying from COVID-19 if they did become infected. What is emergency use authorization for COVID-19 vaccines and treatments, Trial data shows coronavirus vaccines are highly effective, Keep Sharp: Build a Better Brain at Any Age Book. A June report from the Centers for Disease Control and Prevention (CDC) found that hospitalizations for people with COVID-19 were six times as high for patients with chronic health conditions like heart disease, lung disease and diabetes, compared to otherwise healthy individuals. People with type O blood tend to clot less that their peers, Ray says. People with type O blood may be at a lower risk of catching coronavirus and being admitted to hospital by the disease, according to a study from 23andMe, the … They compared the ABO blood group distribution in 2173 patients with COVID-19 from 3 hospitals in Wuhan and Shenzhen, China, with that in the general population in those regions. "While we're not quite to the point where this is ironclad, it's clearly suggestive, and we have not seen anything inconsistent with this. Researchers in Denmark found that among more than 7,400 people who tested positive for COVID-19, fewer individuals had type O blood compared to type A, despite the fact that the two blood types accounted for the same share of the population when compared to a larger control group. They found that people with Type A blood had a 21% greater risk of the disease than their counterparts with other blood types, and that people with Type O blood had a 33% lower risk. It's unlikely that doctors will make treatment decisions based on blood type, Silverstein says, and he cautions that blood type should not be considered on the same level of risk as age, obesity or other underlying health conditions. "It's a repeated, interesting scientific observation that really warrants further mechanistic work," he said. The Canadian study also found those with blood type A or AB had a longer stay in the intensive care unit, a median of 13.5 days, compared with those with blood group O or B, who had a median of nine days. "As a clinician ... it is at the back of my mind when I look at patients and stratify them. The local blood testing lab has seen increased demand from people asking if their blood type puts them at risk of COVID-19. Our Medicare Resource Center can help you make smart choices about the program. AARP is a nonprofit, nonpartisan organization that empowers people to choose how they live as they age. Mounting evidence from Columbia University not only highlights increased infection rates in non-O blood groups, but also that Rhesus positive individuals could … (Patrick T. Fallon/Bloomberg/Getty Images/CNN) The researchers used health registry data from Denmark to analyze the blood types of 473,000 individuals who tested positive for COVID-19 … And if you're blood group O, you're not free to go to the pubs and bars.". Additionally, people with Rh-negative blood were found to have a lower probability of both infection and serious COVID-19 illness than people with Rh-positive blood. Many people don't know their blood type. The provider’s terms, conditions and policies apply. Updated 2029 GMT (0429 HKT) October 14, 2020. The same pattern has been emerging with O blood type tending to be the one that's standing out," Adalja said. They found that blood group wasn't a risk factor for hospitalization or death from Covid-19. Deaths among this population were 12 times as high. By contrast, 44.4% of group A tested positive, while in the wider Danish population that blood type makes up 42.4%. In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. Save 25% when you join AARP and enroll in Automatic Renewal for first year. You can also manage your communication preferences by updating your account at anytime. This, however, does not mean they can't contract the virus or fall seriously ill from it. Clotting has been a major driver of the severity of Covid-19. The results of the present study suggest that while the blood group A might have a role in increased susceptibility to the COVID-19 infection, the blood group O might be somewhat protective. The research provides further evidence that blood type (also known as blood group) may play a role in a person's susceptibility to infection and their chance of having a severe bout of the disease. Why do we have different blood types — and do they make us more vulnerable to Covid-19? Type O is associated with lower risk compared with all the other blood groups. In the meantime, please feel free "If one is blood group A, you don't need to start panicking. And type A patients accounted for a larger proportion of covid … Please enable Javascript in your browser and try "We're starting to see enough now that I think it's an important research question to answer," he said. Please return to AARP.org to learn more about other benefits. Free chapter from AARP’s book by Dr. Sanjay Gupta. | A genetic analysis of COVID-19 patients suggests that blood type might … More specific to the coronavirus is the theory of clotting. Sign up here to get The Results Are In with Dr. Sanjay Gupta every Tuesday from the CNN Health team. Their findings, published in the Annals of Hematology , dispel previous reports that suggested a correlation between certain blood types and COVID-19. "There is a precedent in biology for blood type influencing infection,” Silverstein says. People with certain blood types could be at an increased risk of dying from coronavirus, experts warn Credit: Getty Images - Getty. En español | In the last several months, a number of studies have drawn a connection between blood type and COVID-19 risk, and most have reached the same conclusion: People with type O blood, the most common kind, may have a slight advantage over their peers when it comes to risk for a coronavirus infection and hospitalization or death from COVID-19. Adalja said that blood types and their susceptibility to various infections have been studied in the medical literature before. The researchers found that type O blood was associated with a lower risk for COVID-19, while type A blood was associated with a higher risk. The results were notable: Adjusting for demographics and co-morbidities, the risk for a COVID-19 diagnosis was 12 percent lower for people with type O blood and the risk for severe COVID-19 or death was 13 percent lower, compared to those with A, AB, or B blood types. Nor should people worry unduly about the link between blood type and Covid-19, said Dr. Torben Barington, the senior author of the Danish paper and a clinical professor at Odense University Hospital and the University of Southern Denmark. In the United States. Patients with Type A blood are 50% more likely to need oxygen or require a ventilator, the European study said. However, once infected, blood group type does not seem to influence clinical outcome. Study ties blood type to COVID-19 risk; O may help, A hurt. One explanation: Your blood type is based on proteins, called antigens, that cover the surface of your red blood cells. The researchers found that people with blood type O had a lower chance of severe COVID illness or death compared to people with other blood types. It also reveals that those with a negative blood type (O-, A-, B- or AB-) are, on average, 21 per cent less likely to get the virus than people with a positive type. And a complication seen in many people with severe COVID-19 is blood clots in the small blood vessels of the lungs. Sometimes called COVID toe, the rash resembles frostbite. Get instant access to discounts, programs, services, and the information you need to benefit every area of your life. Canadian researchers reached a similar finding in their retrospective study published in Annals of Internal Medicine. But that doesn't mean you should be more careful; everybody needs to be more careful. Other possible explanations involve blood group antigens and how they affect the production of infection fighting antibodies. 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